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Injection technique and storage are part of safety too

J Eur Acad Dermatol Venereol 36(6):797806 Karacabeyli D et al (2024) Mortality and major adverse cardiovascular events after glucagon-like peptide-1 receptor agonist initiation in patients with immune-mediated inflammatory diseases and type 2 diabetes: a population-based study

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First-line management: Correct technique, rotate sites, apply cool compress, topical hydrocortisone 1% for pruritus

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And some research has raised, if not red flags, perhaps a few yellowish ones