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Many patients initiating tirzepatide are simultaneously making multiple lifestyle modifications, experiencing hormonal changes related to weight loss itself, or may have pre-existing dermatologic conditions that become more noticeable during this period of heightened body awareness

Monthly costs for the GLP-1s often exceed $1K per patient , driving up pharmacy spending across the board

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Retatrutides results have been even more dramatic

The group size was determined by power analysis and our prior work using the same experimental design