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Appropriate immunohistochemical stains or panels can be used to distinguish possible considerations such as lymphoid, epithelial, and neuroendocrine lesions
For most people, the available human data does not support the same concerns that arose from rodent studies regarding GLP-1 receptor agonists and thyroid cancer
PMID: 21030672 | doi:10.1152/japplphysiol.00945.2010 Zivanovic-Posilovic G et al
Oxidative stress is involved in the pathophysiology of PD as excessive production of reactive oxygen species (ROS) contributes to dopaminergic neuronal damage, which is susceptible to oxidative injury due to high metabolic activity and dopamine metabolism
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However, a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 remains a contraindication to GLP-1 RA therapy
