Vitamin B12 has a very low risk of toxicity, so there's really no upper limit to how much you can take without harm

Rare: may affect up to 1 in 1,000 people Acniform and bullous eruptions (acne-like and blistery skin eruptions) Not known: frequency cannot be estimated from the available data Headache, dizziness Nausea (feeling sick), vomiting, diarrhoea Malaise (feeling unwell) Rash, itching Injection site reactions including injection site pain, injection site erythema, injection site pruritus, injection site induration, and injection site swelling (Reactions at the site of the injection) Exanthema (a widespread skin rash) Chromaturia (unusual coloured urine) Fever Hot flushes (a feeling of intense heat with sweating and rapid heartbeat) Chills (feeling of coldness accompanied by shivering) Paraesthesia (feeling of pins and needles) Tremor (tremble or shakes) Hypokalaemia (decreased potassium levels in the blood) Reactive thrombocytosis (body produces too many platelets) Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse

By blocking NNMT, it may support cellular NAD+ levels and metabolic function
Navigating the landscape of B12 Shots & B12 Injections: The Good, Bad, and Alternative
The points below describe potential research-observed benefits , not approved medical or therapeutic claims
Competitive athletes should be aware of WADAs S0 prohibition on non-approved substances