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* Correspondence: Roberto Codella, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

That is a remarkable outcome, but the distinction matters: these peptides were not FDA-approved today, and pharmacies are not suddenly authorized to begin compounding them tomorrow

Rotating between thigh, abdomen, and upper arm helps reduce skin irritation and the small bumps (lipohypertrophy) that can develop from injecting the same spot repeatedly

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Most patients experience gradual improvement over time, though a minority may have persistent symptoms requiring dose adjustment or treatment review

If weight remains stable, reduce another step and repeat