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These medications: Decrease pro-inflammatory cytokines including TNF-, IL-6, and IL-1 9 Reduce macrophage infiltration in tissues 40 Block NF-B activation, a key inflammation controller 41 Switch macrophages from pro-inflammatory M1 to anti-inflammatory M2 type 40 These effects show promise for various joint conditions

For instance, the hormone glucagon-like peptide-1 (GLP-1) stimulates insulin release and inhibits glucagon release (which raises blood glucose)

Prescribing these medications is far more than simply writing a prescription, Jaisinghani says

all subjects had an additional health condition related to obesity, and nearly 20% of them had type 2 diabetes

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The market was valued at USD 18.75 Billion in 2022 which is expected to reach USD 133.5 Billion in 2030