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Beginning with a lower dose allows the body to adjust to changes affecting appetite and digestion

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Whilst most patients tolerate the medication well, approximately 12% experience skin reactions

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Hong JY, Lee CY, Lee MG, Kim YS

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These 3 genes, X box binding protein 1 ( XBP1 ), activating transcription factor 4 ( ATF4 ), and ATF6 , are regulators of the 3 pathways of the unfolded protein response (UPR) (57, 58)

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Vadher K, et al

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The disadvantage is precision at lower doses

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