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Effects of Endotoxins on Methylation Pathway and Glutathione Production Endotoxin exposure can increase the production of pro-inflammatory cytokines, such as TNF-, which can lead to an upregulation of CBS enzyme

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It is first reduced with sodium borohydride to ethyl -bromo--hydroxybutyrate, which then reacts with trimethylamine to form a quaternary ammonium salt, ethyl bromotrimethylammonio--hydroxybutyrate