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The tolerability profile is generally favorable, with most patients experiencing manageable side effects

Subchronic administration of d-allulose to HFD-fed mice Male C57BL/6J wild-type mice and male Glp1r KO mice fed HFD for 5 weeks or longer were orally treated with d-allulose (1 or 3 g kg 1 ) or water (10 ml kg 1 ) once daily at the onset of LP (7:30) or DP (19:30) for 9 or 10 days

doi:10.1001/jamaophthalmol.2025.1455

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It subsequently suppresses the hepatic LPSTLR4NF-B signaling pathway, reducing inflammation and fibrotic progression

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