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When NNMT is overactive as it tends to be in fat tissue, and increasingly with age and obesity it siphons off the very raw material your cells need to keep NAD+ topped up

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Lipids 1862 , 11781187 (2017)

Understanding vitamin B12's water solubility helps explain certain aspects of its metabolism, but deficiency risk is primarily related to inadequate dietary intake or malabsorption issues

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