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doi:10.1016/S0021-9258(18)65950-2
Although the mRNA abundance of hepatic Gck , the enzyme that phosphorylates glucose to produce glucose-6-phosphate, was significantly upregulated in Dpp4 / mice compared with livers of control mice (Figure 1E), transcript levels of the gluconeogenic enzymes, Pck and G6p , were unchanged (Figure 1E)
Off-label use for general belly fat, metabolic health, or bodybuilding is not backed by large trials
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Patients should undergo baseline assessment including HbA1c and renal function
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