They might have decreased kidney function, drug interactions, and more malabsorption issues
A canonical pathway diagram is not compound-specific evidence
When malabsorption is the issue, simply eating more B12-rich foods or taking standard oral supplements might not be enough
If you notice signs of anaphylaxisswelling of your tongue, face, or throat, difficulty breathing, or difficulty swallowingafter getting a B12 injection, call 911 or head to the closest emergency room immediately
A population-based study in 3,884 elderly men and women with depressive disorders found that those with vitamin B 12 deficiency were almost 70% more likely to experience depression than those with normal vitamin B 12 status (98)
It is used in the treatment and prevention of vitamin B12 deficiency in patients with conditions such as:_ Addisonian (pernicious) anemia Malabsorption Atrophic gastritis Prolonged treatment with metformin Small bowel bacterial overgrowth (SIBO) Total or partial gastrectomy Infection with the fish parasite Diphyllobothrium latum Helicobacter pylori infection Pancreatic dysfunction Pancreatic or bowel malignancy Dietary deficiency (e.g