We all know this to be true
doi:10.3390/molecules14072317 Bahrami K, Nazari P, Sepehrizadeh Z, Zarea B, Shahverdi AR
Aspirin is such a drug, and it now is recognized that it can safely be given to individuals with Class II and III G6PD variants
2011)were the first to demonstrate region-specific alterations in the oxidative damage marker 3-nitrotyrosine (3-NT) in postmortem brains of individuals with autism, showing that regions such as the orbitofrontal cortex, Wernickes area, the cerebellar vermis, and the cerebellar hemispheres exhibited distinct levels of this biomarker, reflecting region-specific redox signatures
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The breakdown of oral glutathione in the gut is driven partly by the enzyme gamma-glutamyltransferase, which is why a conventional tablet raises blood glutathione only slightly (Buonocore et al., Oxidative Medicine and Cellular Longevity 2016, PMID 26649136)