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de Boer IH, DCCT/EDIC Research Group (2014) Kidney disease and related findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

Research has found that carnitine deficiency can cause smooth muscle dysmotility (changes in speed, strength, or coordination) of the gastrointestinal tract (similar to what it does to muscle metabolism, causing muscle weakness), which can cause gastrointestinal discomfort and changes in the microbiota ( gut dysbiosis ), as well as constipation

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et al., 2003)

JAMA, 327(6), 534