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Unregulated substances that are not meant for human use, including IGF-1 LR3, can also have unknown or potentially debilitating side effects

Notably, Arg1 expression in MDSCs contributes to arginine depletion in the microenvironment, further inhibiting T-cell antitumor function and reducing their survival

Harris, I., Treloar, A., Inoue, S., Sasaki, M., Gorrini, C., Lee, K

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Ostadrahimi, A., Taghizadeh, A., Mobasseri, M., Farrin, N., Payahoo, L., & Beyramalipoor Gheshlaghi, Z