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Description

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And oxidative stress may be one of the key drivers behind it

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Health Effects of Dietary Risks in 195 Countries, 1990-2017: a Systematic Analysis for the Global Burden of Disease Study 2017

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The endogenous mechanism is triggered by the depletion of intracellular glutathione (GSH) and inactivation of GSH peroxidase 4 (GPX4) (Masaldan et al., 2019), cardiomyopathy (Timmers et al., 2020), atherosclerosis (Ouyang et al., 2021), liver injury (Tonnus et al., 2021), or related pathological cell death

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