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Medications Blood Sugar-Lowering Medications (e.g., insulin, metformin): NAD supplements can affect glucose metabolism and alter insulin sensitivity, potentially making these medications less effective or requiring dose adjustments

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Not all patients benefit equally from GLP-1 therapy, and individual factorsincluding baseline metabolic function, comorbidities, and genetic backgroundshape treatment selection

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In that report, the incidence of pancreatic cancer was also 2.9 and 2.7 times greater with exenatide and sitagliptin, respectively, compared to other oral antidiabetic medications