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Rather than forcing changes through stimulants or blocking nutrient absorption, it appears to work by helping regulate the body's natural satiety mechanisms

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PMID: 32945357

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In addition, a greater effect of tirzepatide on dose-dependent body weight reduction versus semaglutide was observed (least-squares mean estimated treatment difference of -1.9 kg, -3.6 kg, and -5.5 kg for the three doses

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