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The cosmetic form (listed as Copper Tripeptide-1 on ingredient labels) is widely used in skincare and is regulated as a cosmetic, not a drug

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Likewise, in cultured neurons, excitotoxicity is associated with increased glycolysis at expense of reduced PPP activity (Rodriguez-Rodriguez et al., 2012)

No systemic copper toxicity at standard doses (Pickart & Margolina, 2018)