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Approximate dose correspondence (not equivalence) Notice how each semaglutide dose maps to a range of tirzepatide doses, not a single number

While insulin induces tissue uptake of glucose to lower blood glucose levels, glucagon stimulates the conversion of glycogen to glucose resulting in an increase of blood glucose

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According to the FDA prescribing information, the most frequent adverse effects of semaglutide include nausea, vomiting, diarrhea, abdominal pain, and constipation

It says intrinsic factor, the glycoprotein that binds B12 for absorption in the terminal ileum, may be suppressed during chronic use