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If side effects become intolerable at any dose level, dropping back to the previous dose for two to four additional weeks before attempting escalation again often allows successful progression

This procedure is no different from giving blood for a blood test

Once reconstituted with bacteriostatic water, keep refrigerated and handle under sterile laboratory conditions

Phase 2 clinical data showed that starting at lower doses (1-2mg) partially mitigated gastrointestinal side effects compared to more aggressive starting doses

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Include 150-300 minutes of moderate-intensity activity per week, such as brisk walking, cycling, or swimming