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The efficacy endpoint for all of these trials was the incidence of laboratory-confirmed clinical influenza defined as meeting all the following criteria (all signs and symptoms must have been recorded within 24 hours): oral temperature greater than or equal to 99.0F (37.2C), at least one respiratory symptom (cough, sore throat, nasal congestion), at least one constitutional symptom (aches and pain, fatigue, headache, chills/sweats), and either a positive virus isolation or a four-fold increase in virus antibody titers from baseline

Some state regulators have joined Novo and Lilly in raising safety concerns regarding some compounded versions

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Potential Impact on Metabolism: There's ongoing research into how GLP-1 medications might impact metabolism, potentially leading to increased energy expenditure or fat burning

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