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Moreover, administration of N-acetyl cysteine (NAC) or ascorbate, antioxidants that increase tissue glutathione levels, abolished ovariectomy-induced bone loss, while L-buthionine-(S,R)-sulphoximine (BSO), a specific inhibitor of glutathione synthesis, caused substantial bone loss

A study by Ozbalci et al

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C., Hay, W

We also observed a 23-fold increase in CHAC1 transcription with GSTO1 knockdown but not with C1-27 treatment

Transsulfuration CBS combines homocysteine with serine to form cystathionine