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Tesamorelin is a 44-amino-acid synthetic analog of growth hormone-releasing hormone (GHRH), formed by adding a trans-3-hexenoic acid group to the native GHRH(1-44) sequence

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Although physical therapy and drug management still dominate OA treatment, the establishment of a stepwise nutritional intervention plan is believed to assist in delaying OA progression, reducing drug use, and avoiding surgical risks

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