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BPC-157 has been a subject of FDA attention in compounded pharmaceutical contexts, and dietary supplement classifications can change

2025 systematic review in HSS Journal screened the full BPC-157 musculoskeletal literature through June 2024 and found a large preclinical base tendon, ligament, muscle, bone, and nerve injury models but only one published human exposure dataset, the small open-label knee-pain case series

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Therapeutic Goods Administration

Experimental work examining angiogenic responses during muscle and tendon healing reported increased expression of angiogenesis-associated markers such as vascular endothelial growth factor (VEGF), CD34, and factor VIII within injured tissues following BPC-157 exposure [6]