At 72 weeks, Zepbound beat Wegovy on both the primary endpoint and all five key secondary endpoints in the trial of adults living with obesity or being overweight with at least one weight-related medical problem and without diabetes
however, because Mounjaro is a dual-action medication, it mimics GLP-1 as well as another hormone called GIP
Light to moderate exercise like walking, stretching, or resistance training can actually reduce body aches rather than make them worse
That framing, while not wrong, misses most of what is actually happening
The incretin hormones, principally glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released into the circulation in response to nutrients and facilitate insulin secretion in a glucose dependent manner
A quick note on why a dietitian is writing this: I went down this same rabbit hole after seeing oral versions of these peptides marketed heavily to firefighters