7779 Furthermore, a recent report demonstrated that exogenous GSH at physiological concentration (10 mM) enhanced susceptibility to chloramphenicol, novobiocin, and tetracycline, while decreasing susceptibility to ciprofloxacin, erythromycin, and kanamycin in A
Statistical significance was assessed by by ordinary two-way ANOVA in a , and by unpaired two-tailed t-test in b , c
NAC serves as a precursor to cysteine, which is a limiting substrate for the synthesis of glutathione
Unlike intravenous glutathione, which provides an immediate, massive spike in plasma levels that fades within a few days, oral supplementation with Setria is designed for long-term, cumulative cellular uptake
PMID 6844712
The catalytic activity of GR is a two-step process