The classical pathway is initiated by pathogenic stimuli, which activate pattern recognition receptors (PRRs) along with caspase recruitment domain- or pyrin domain-containing proteins (159, 163)
Nonetheless, in patients at high risk of sarcopenia, tailored management including nutritional optimization and concurrent resistance training should be considered to mitigate potential adverse consequences during pharmacologically induced weight loss [20]
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Semaglutide is a medication originally developed for type 2 diabetes that is now increasingly used for weight management due to its proven benefits on appetite control and metabolism
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Selhub J, Jacques PF, Bostom AG, Wilson PW, Rosenberg IH