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The male SHR model showed that intestinal flora and its metabolites are closely associated with hypertension-related nephropathy, and the results indicate that reduced levels of SCFAs, inflammatory factor release, and blood pressure disturbances occur in the process (174)
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Furthermore, these nanocarriers are capable of depleting GSH levels in the tumor microenvironment to augment stress on cells and induce cell death pathways, including ferroptosis, making cancer cells sensitive to treatment Fig
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