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The NIH Vitamin B12 Fact Sheet for Health Professionals notes that oral supplementation is appropriate for many patients who do not have intrinsic factor deficiency

Our bodies however are only able to absorb 2g of vitamin B12 per meal, therefore additional supplementation may be beneficial

Low energy levels and a slowdown in fat burning are the two primary challenges you may encounter during your weight loss journey

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Vitamin B12 shots should be taken only in prescribed doses and administered by a licensed medical practitioner

Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement