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It is engineered with two structural modifications relative to the 70-residue native protein: a substitution of arginine for glutamic acid at the third position and a 13-amino-acid extension at the N-terminus, giving a total length of 83 amino acids

Regul Pept 185:18 Lu WJ, Yang Q, Sun W, Woods SC, DAlessio D, Tso P (2007) The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate

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Since alterations of mitochondrial functions have been related to psychiatric disorders at both clinical and preclinical levels ( / rats could be due, at least in part, to an imbalance of mitochondrial activity related to the congenital lack of the 5-HTT

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A recent prospective case-control study (17) showed that in a 10-year period, regardless of the level of baseline TMAO, the final increase in TMAO was significantly associated with an increased risk of CHD, and the TMAOCHD relationship could be improved by dietary changes (17)