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Comprehensive biochemical testing demonstrates that 5 amino 1mq does not inhibit structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA methyltransferase 1 (DNMT1), or protein arginine methyltransferase 3 (PRMT3)

10.1038/s41593-020-00783-4 131 Eslami ShahrbabakiM.SabouriS.SabahiA.BarfehD.DivsalarP.EsmailzadehM.et al

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Molecular docking experiments were conducted with four target proteins (COX-2, MMP-9, TNF-, and MPO) to explore the interaction between mesalamine (compound 36, Figure 26) and its coumarin derivative, MS-CU

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