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Plateau in weight loss, tolerability, formulary access, and comorbidity changes each have different implications for which drug to target and what to expect

Polycystic Ovary Syndrome (PCOS): Weight loss from GLP-1s can help improve insulin resistance, a key driver of PCOS

When AMPK senses low energy, it works quickly to restore it inside cells, which it does by redirecting metabolism to take sugar in the form of glucose from the blood and pull it into cells to be used for energy

Routine liver function monitoring is not required for patients without pre-existing liver disease, though baseline assessment may be appropriate in certain clinical situations

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