The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes [1] [2]
00:10:48 Vickie Danaher In terms of serious safety concerns, orforglipron carries the same precautions and warnings as other GLP-1 agonists, so rare risks of thyroid tumors, pancreatitis, and gallbladder disease, for example
In the meantime, these tips might help: Together, these management techniques can help you feel more like yourself again while your body adjusts to a GLP-1 agonist
Not approved for human use, not for therapeutic applications, and not for in vivo studies in humans
We hypothesized that replacing GIPRs C-terminal tail with that of GLP-1R would result in a receptor that signals and internalizes like GLP-1R and vice versa
It's crucial for individuals to discuss any allergies or medical conditions with their healthcare provider before starting treatment