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A recent metanalysis [87] has assessed the impact of oral antidiabetic drugs (OADs) and GLP-1 receptor agonists on left ventricular diastolic function in patients with type 2 diabetes, the findings indicated that, compared to placebo and OADs, only liraglutide significantly improved left ventricular diastolic function
In the gastrointestinal tract, metformin effects glucose uptake and absorption, increases glucagon-like peptide-1 (GLP-1) secretion, alters the composition and structure of the gut microbiota, and modulates the immune response
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You need to take OTC supplements
