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SASP (senescence-associated secretory phenotype) results revealed that FOXO4-DRI downregulates the levels of IL-1 , IL-6 , IL-8 , and TNF- (Figure 4H)

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SAM and SAH These markers help clarify methyl-donor capacity and inhibition of methyltransferase reactions

A weak enzymatic activity of class II HsGRX5 after deletion of the loop was also reported in an independent study which used Cys-SG as a substrate 15