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To create viable therapeutics, researchers had to engineer GLP-1 analogs that resist enzymatic breakdown and persist long enough to exert physiological effects

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation

caldus Markerless gr knockout mutant was generated as described previously with minor modifications (as shown in Figure 1) (Wang et al., 2016)

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Nevertheless, as these models allow controlling the medium flow, dynamic BBB models were successfully applied for the investigation of the ischemia-induced injury (Cucullo et al., 2008) and antiepileptic drugs (Cucullo et al., 2007)

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