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Endocrinology 155 , 726735 (2014)

3.3.5 Myeloid-derived suppressor cells The bone marrow-derived heterogeneous cell populations with immunosuppressive functions are produced in large quantities under the stimulation of various factors, including cancer and inflammation

That same document makes a point worth repeating: mild-to-moderate gastrointestinal symptoms are not an indication that treatment is going wrong

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