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Based on the impact of PfK13 mutations on hemoglobin uptake and GSH levels in the parasite, one can hypothesise that a decrease in redox-active ferrous heme in artemisinin resistant parasites leads to elevated GSH within the cell, potentially making them more tolerant to artemisinin-induced oxidative stress

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In my clinical experience low or insufficient b12 is quite common

Refrences 1Averill-Bates DA

The hair cycle moves through anagen (growth, lasting years), catagen (a short transition) and telogen (rest, followed by shedding)