Additional information Peer review information Primary Handling Editor: Christoph Schmitt
This is an effort where industry and academia need to closely collaborate to find the right patient cohorts, which is not an easy task in rare disease. Meanwhile, he wants clinicians to know that tirzepatide is a good option for treating obesity, hyperphagia, MASLD, and type 2 diabetes in AS, but because of the rapid therapeutic response it produces, patients require careful monitoring
Mounjaro (tirzepatide) [package insert]
Regulatory Status GLP-3 (Reta) (LY3437943) is an investigational compound developed by Eli Lilly
A number of synthetic analogs and research compounds exist in this category, including semaglutide-class and tirzepatide-class sequences, as well as dual- and triple-agonist research peptides
10.1016/s0140-6736(23)01301-6 59 OrskovC.HolstJ