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However, researchers and clinicians have observed its potential in a much broader population, especially in the context of: Visceral adiposity (deep belly fat) Growth hormone deficiency Cognitive aging Cardiometabolic risk reduction Its appeal lies in the ability to elevate IGF-1 (insulin-like growth factor-1) levels while preserving the bodys natural feedback mechanisms
The conversation about long-term use needs to happen before starting the protocol, not after reaching goal weight
Even with qualifying BMI and documented comorbidities, most commercial insurers still deny semaglutide for weight loss indication, prioritizing diabetes-only use
More human studies are necessary, but one study of 90 people with high LDL cholesterol found that daily allulose intake of 5 to 15 grams for almost one year improved fatty liver scores
Grunewald KK, Bailey RS
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