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Metabolic improvements often become measurable during this period

Most likely, this is a result of misclassification of prevalent GLP-1 RA users as incident users, which may be the case for patients who receive prescriptions from pharmacies and hospitals not included in the LRx country-specific databases and who subsequently switch to those that are included

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This work was supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) Grant Number JP15K19036 (SH), JSPS Grant-in-Aid for Young Scientists Grant Number JP19K16271 (SH), Japan Science and Technology Agency (JST) ACT-X Grant Number JPMJAX201A (SH), RIKEN FY2018 Incentive Research Projects (SH), and Naito Grant for female scientists after maternity leave (SH)

The rise of compounded GLP-1 drugs, counterfeit supply chains, and off-label use has driven regulatory warnings and enforcement activity

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