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doi: 10.1016/j.ajog.2005.08.047 120 FujitaT

It raises TGF-beta2 a key anti-inflammatory cytokine and delivers additional lactoferrin, a bioactive protein known for inhibiting the growth of disease-causing microorganisms

This can reduce the risk of developing type 2 diabetes, cardiovascular disease, and other obesity-related conditions

Coverage for weight loss medications vary

If people are unable or unwilling to continue with drug treatment or maintain effective lifestyle changes, the initial health improvements will not be sustained, limiting long-term population-level benefit. Clinicians also need to be clear in communicating to patients that obesity is a chronic condition requiring long-term management

A separate 2024 meta-analysis (Alshammari et al.) confirmed the same conclusion, further strengthening the evidence base