doi: 10.3389/fsurg.2025.1618362 Received 25 April 2025 Accepted 28 August 2025 Published 15 September 2025 Volume 12 - 2025 Edited by Rafael De La Garza Ramos, Albert Einstein College of Medicine, United States Reviewed by Marica Eoli, IRCCS Carlo Besta Neurological Institute Foundation, Italy Hajnalka Rajnai, Semmelweis University, Hungary Zhenhua Li, Brigham and Women's Hospital and Harvard Medical School, United States Updates Copyright 2025 Guranda, Wach, Gresir, Braune, Kuzman and Nestler
Always use a new needle for every dose and remove it before storing the pen
While not mandatory, CGMs significantly reduce hypoglycemia risk by enabling early detection and intervention during the first weeks of GLP-1 therapy
Why Individual Receptor Sensitivity Matters for Side Effect Risk Your genetic makeup influences how strongly your GLP-1 receptors respond to medication, which affects both efficacy and side effects
Oral Contraceptives : Slower absorption can reduce effectiveness
Semaglutide should not be stored at room temperature