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The glucose dependent insulinotropic polypeptide response to oral glucose and mixed meals is increased in patients with type 2 (non-insulin-dependent) diabetes mellitus
Until retatrutide has equivalent data, semaglutide is the evidence-based choice for people with established heart disease
Genetic polymorphisms in NAT2 (N-acetyltransferase 2), TPMT (thiopurine methyltransferase), and glutathione S-transferase genes create phenotypic differences
Weight regain is common if no maintenance habits are in place
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