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For example, mitochondrial muscle diseases cause NAD + deficiency, detectable both in the muscle and blood 15,16

In some individuals, prolonged use may contribute to gastroparesis, cyclic vomiting, or impaired nutrient absorption (25)

While obesity can lead to other conditions, it is also an independent disease worthy of pharmacological interventions, even when it affects nondiabetic people who may otherwise be characterized as metabolically healthy, the researchers say

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