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Bhattacharya et al

Anderl 2013)

Research demonstrates that postmenopausal women experience a 9% decrease in total 24-hour energy expenditure and a 30% reduction in spontaneous physical activity energy expenditure.[1] The metabolic consequences are profound: estrogen deficiency worsens insulin resistance, which is further exacerbated by the age-related increase in cortisol that promotes gluconeogenesis

However, the safety and efficacy of such combinations require careful evaluation

10.1016/j.jdermsci.2015.09.003 232 XinL.GaoJ.LinH.QuY.ShangC.WangY.et al (2020)

Lithium, valproic acid (VPA), and carbamazepine (CBZ) are used as anti-bipolar drugs