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Products of conjugated acyl chain oxidation include aldehydes, peroxides, and high molecular weight covalent polymers 45,46,47,48,49

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GHRH receptor agonism leading to increased pituitary GH secretion

189 Further, ME1 treated with the inhibitor (piperazine-1-pyrrolidine-2,5-dione) has little effect on normal rat intestinal epithelial cells but strongly suppresses human CRC cell growth by targeting ME1 NADP + -binding site and reducing the NADPH level