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The combination of different drugs to achieve improved efficacy and reduced toxicity represents a potential direction for the development of ferroptosis-targeting drugs in the future

Tirzepatide and retatrutide (single molecule): A single engineered molecule that hits multiple receptors simplifies the formulation to one compound with one pharmacokinetic profile, and allows the balance of receptor activation to be tuned at the molecular-design level

There is no doubt about the malignant and metastatic potential of melanoma tumorigenesis, and the heterogeneity and plasticity of their cells