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Polymorphisms in GLP-1 receptor genes, incretin pathway enzymes, and appetite regulation circuits influence individual response
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The enzyme dipeptidyl peptidase-4 (DPP-4) rapidly inactivates GLP-1 by removing two N-terminal amino acids and an intact N-terminal is needed to bind to the GLP-1 receptor [35]
doi: 10.1038/s41392-021-00670-9
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